Although it is counter-intuitive, sleep and exercise present the brain with similar energy challenges, that of optimal provision of cerebral energy, via the liver. Failure to optimally provision cerebral energy in each of the above events results in chronic metabolic stress, and increased risk of metabolic diseases.
During the nocturnal fast this failure to pre-provision the liver (and therefore the brain), results in chronic activation of the HPA (stress) system and increased risk of metabolic syndrome (diabetes/obesity/heart disease and alzheimer’s disease).
The same ‘liver blind’ approach in sport results in osteoporosis, infertility, increased risk of infections and in American professional footballers increased risk of diabetes from age 35.  Italian footballers express 5 times the national average for motor neurone disease.

This talk focuses on the way to optimally provision cerebral energy during exercise and during the nocturnal fast. The Exercise Theory of Relativity takes Einstein’s beautiful formula E = MC2  and reverses it to E = CM2

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